Left frontal glioblastoma can be treated surgically, which can relieve symptoms and improve survival. However, because of its high degree of malignancy, survival time is shorter even after surgical treatment. Glioblastoma is a malignant epithelial tumor that originates in the white matter and grows rapidly and easily necrotic by infiltration. Glioblastoma has a short course, and symptoms of high cranial pressure such as optic nerve papillary edema are more obvious. It is most common in the cerebral hemispheres and may invade the contralateral cerebral hemisphere, thalamus, and basal nuclei via the corpus callosum. It can be treated surgically by removing the tumor, lowering the intracranial pressure and relieving the compression on cerebral nerves. However, glioblastoma is highly malignant, and even after surgical treatment, radiotherapy, and chemotherapy, most of its survival time is only about 1 year. When patients suffer from glioblastoma, it is recommended that they be diagnosed and treated under the guidance of a professional doctor.