Nodular hyperdense shadow in the middle lobe of the right lung is an imaging result, which can be caused by many reasons, such as inflammation of the lungs, tuberculosis, tumors and other diseases. 1. Inflammation of the lungs: Inflammatory reaction of the lungs due to infection by external pathogenic bacteria may also lead to the phenomenon of nodular hyperdense shadow in the middle lobe of the right lung, which is mostly accompanied by symptoms such as chest pain, coughing, fever, and dyspnea. 2. Tuberculosis: It is due to the inflammatory reaction of the lungs caused by the infection of tuberculosis bacillus, which may also be manifested in the findings of nodular high-density shadow in the middle lobe of the right lung. It may be accompanied by low-grade fever, night sweats, cough, hemoptysis and other symptoms. 3. Tumor: benign tumors or malignant tumors of the lungs may also show nodular hyperdense shadow in the middle lobe of the right lung. Tissue biopsy and other auxiliary examinations are needed to confirm the diagnosis with clinical symptoms and active systematic treatment.