Hepatitis Virus Test Hepatitis B Surface Antibody Positive is produced by hepatitis B vaccination or previous infection with the hepatitis B virus, and usually indicates that the body has the ability to resist the hepatitis B virus. Hepatitis B Virus Test Hepatitis B Surface Antibody is a protective antibody against the hepatitis B virus, which indicates that the body is immune to the hepatitis B virus. It is usually positive after hepatitis B vaccination. Positive hepatitis B surface antibodies can also occur after a previous infection with the hepatitis B virus and the body has recovered, but may also be accompanied by positive e-antibodies and core antibodies during the recovery period after the original infection. It is not possible to diagnose a disease on the basis of one indicator, but rather on the basis of the clinical history and other indicators.