Esophageal mucosa usually regenerates after stripping. Esophageal mucosal stripping usually refers to endoscopic esophageal mucosal stripping, which is a surgical method to remove the diseased mucosa with the assistance of endoscopy. The removed mucosal tissue can also be biopsied for pathological examination, and it is mainly used for the diagnosis and treatment of early esophageal cancers, giant flat polyps, and submucosal tumors. Endoscopic esophageal mucosal dissection removes the diseased mucosa, which usually only involves the submucosal layer without involving the muscle layer and other tissues. The esophageal mucosa belongs to the epithelial tissue, which is a kind of renewable cell with strong regenerative ability, and it can usually regenerate and recover after peeling. After endoscopic esophageal mucosa stripping surgery, patients need to fast, after the patient’s exhaust can begin to drink a moderate amount of warm water under the guidance of the doctor, if there is no obvious discomfort, you can gradually open the diet, usually from a liquid diet to a semi-liquid diet, and eventually return to a normal diet. If there is any obvious discomfort after endoscopic esophageal mucosal dissection, it is necessary to consult a doctor in time and receive treatment actively to avoid delaying the condition.