Intermediate stage pancreatic moderately differentiated cancer has the possibility of clinical cure, whether it can be cured or not is related to the patient’s physical quality, treatment plan and other factors. Middle-differentiated cancer of cardia is a special type of gastric cancer, middle-differentiated refers to medium degree of malignancy of the tumor, and middle stage often suggests that the patient’s tumor infiltration is deeper, or there are local lymph node infiltration, etc. It is generally difficult to achieve clinical cure, but there is still a possibility of this, and the 5-year survival rate is around 40%-70%. For patients with middle stage pancreatic differentiated cancer without distant metastasis, radical surgery can be adopted, and according to the condition of the patients, they can choose preoperative radiotherapy or postoperative radiotherapy, some of the patients can get more than five years’ survival, but some of the patients will suffer from recurrence and metastasis after surgery, and they can be relieved of the symptoms and prolonged the patients’ life by further radiotherapy, chemotherapy and other comprehensive treatments. It is recommended that patients actively cooperate with doctors to achieve clinical cure and improve the quality of life.