Breast cancer to the ulcerative stage, is the advanced stage of breast cancer, it is recommended to remove the primary lesion according to the primary disease, the remaining ulcerative wounds are relatively well treated. If only treating the pure cancerous wound, the treatment is very difficult because negative pressure treatment of cancerous wound can not cure it and even accelerate the growth of cancer. Therefore, the fundamental method is to remove the primary lesion first, and then treat the ulcerated wound with various functional dressings or negative pressure treatment. If granulation tissue grows after negative pressure treatment, the wound can be closed by skin grafting. Therefore, the most fundamental thing is to remove the primary lesion, if not, the ulcer can not heal and can not be treated. Conventional treatment of the wound is to clear, disinfect, change and dress the wound, avoid contact with water, and treat with palliative dressing changes with functional dressings, which can be palliative for patients who do not want to undergo surgery clinically.