The most important cause of ischemic changes in the white matter of the brain is due to cerebral atherosclerosis. The formation of cerebral atherosclerosis is also associated with high blood pressure, high blood lipids, diabetes and age, as well as poor lifestyle such as smoking and alcohol consumption, all of which may lead to atherosclerosis of the blood vessels in the brain. The narrowing of cerebral blood vessels and the slowing of blood flow may cause ischemic changes in the white matter of the brain. In CT, the main manifestation is patchy hypointense shadow and white matter laxity, which is also called cortical atherosclerotic encephalopathy. Patients may have memory loss, inattention, dementia, and behavioral changes, and in severe cases, even coma and death. A mild ischemic change in the white matter of the brain, the patient will mainly show this dizziness, not awake feeling, treatment is mainly to prevent cerebral atherosclerosis, active control of blood pressure, blood lipids, blood sugar, blood homocysteine, to stop smoking, limit alcohol.