Ischemic changes in the white matter of the brain are caused by chronic lack of blood supply to the brain, resulting in demyelination of nerve fibers in the white matter of the brain. Patients with ischemic changes in the white matter of the brain will show lamellar hypointense shadows in the lateral ventricles on both sides of the head on CT or magnetic resonance imaging. This is mainly due to chronic cerebral blood supply deficiency and cerebral arteriosclerosis, so when patients have cerebral white matter ischemic changes, they must promptly regulate the risk factors of cerebral arteriosclerosis. Strict control of blood pressure, blood lipids, blood sugar, blood homocysteine, and patients should quit smoking, limit alcohol, and have a low-salt, low-fat diet to avoid aggravating cerebral artery atherosclerosis. Because of the serious ischemic changes in the white matter of the brain, it will lead to memory loss, cognitive impairment in severe cases, and patients can not easily control urine and stool, prone to urinary and fecal incontinence and other problems.