The efficacy of ketoconazole is antifungal, and its role is to treat various diseases caused by fungi. Ketoconazole is commonly used in the form of hair lotion, cream, ointment, etc. It can inhibit the biosynthesis of fungal cell membranes, thus exerting antifungal effects, and is mostly used for the treatment and prevention of scalp fungal infections, such as furuncle rash, seborrheic dermatitis, tinea cruris, or superficial fungal infections, such as tinea cruris, ringworm, tinea cruris, and so on. It should be noted that the use of any preparation of compound ketoconazole is prohibited for those who are allergic to any component of this drug, pregnant women, lactating women, pediatric patients, patients with viral infections, and some patients may experience adverse reactions such as burning sensation of the skin, itching, dryness of the hair, alopecia, folliculitis, hyperpigmentation and hirsutism during the use of this drug, and should consult a doctor in time if the discomfort is more serious. Patients should follow the doctor’s instructions to use any preparation of compound ketoconazole, avoid self-medication blindly, so as not to affect the condition.