Efficacy of oral rotavirus vaccine

Rotavirus enteritis is a common disease affecting children from 6 months to 3 years of age. Rotavirus vaccination is the most effective and economical medical tool to prevent rotavirus enteritis. It is different from other vaccines in that it cannot be given by injection, but is given orally. The protection period after oral vaccination with the live rotavirus vaccine is usually one year and up to one and a half years, so in order to avoid contracting pediatric autumn diarrhea, it is important to get vaccinated once a year between the age of 2 months and 3 years. The vaccine, when administered orally, acts to stimulate the body to develop immunity to group A rotavirus and is used to prevent diarrhea caused by group A rotavirus in infants and children. Antibodies are generally produced 2 weeks after administration of rotavirus vaccine, with antibody concentrations peaking at 4 weeks and protection against severe diarrhea reaching more than 90%. There are no serious side effects after oral administration of this vaccine, and only a few children may experience mild diarrhea and vomiting, which will disappear in 2-3 days. For children under 3 years of age who receive the vaccine, after 5 days of the first dose, some may experience low grade fever, loss of appetite, restlessness and reduced activity; while the second dose has only mild fever; these phenomena rarely occur by the third dose.