How much do you know about kidney transplantation?

  At present, there are not a few patients who need kidney transplantation, mainly cadaveric kidney transplantation in China. The one-year survival rate of transplanted kidney is above 90%, the 5-year survival rate is above 70%, and the survival time is above 50% in 10 years. Kidney transplantation between living bodies has become very common abroad. In contrast, very few living transplants have been performed in China, only 1% to 2%. Compared to cadaveric kidney transplantation, living kidney transplantation results in faster recovery of kidney function and longer survival time.   Most patients with chronic renal failure can undergo kidney transplantation, but they must undergo a comprehensive and rigorous examination before surgery. Patients with active hepatitis, tuberculosis, ulcers and other diseases are not suitable for kidney transplantation because, except for the donor kidney who is the patient’s identical twin, other patients need to take hormones and other anti-rejection drugs for a long time after the operation, and these drugs will have an accelerating effect on the deterioration of the above diseases. Therefore, doctors will not recommend kidney transplantation for patients with these diseases. In addition, the age of patients who are suitable for the surgery is usually from adulthood to about 60 years old. For elderly people in their 70s and 80s, kidney transplantation is not recommended because they are too old and may not be able to withstand the operation.  What people can donate a kidney Living kidney transplant donors are generally relatives, first of all, they should have the same blood type, tissue matching should also be relatively matched, age between adult and 50 years old, be in good health, and both kidneys in the body must be functioning normally. Hospitals are very cautious in performing living kidney transplants, telling both parties of the possible adverse consequences, such as after Zhang donates one kidney, the other kidney can not be out of order, otherwise they may have to go back to the kidney transplant.  And for doctors, the risk of living kidney transplantation is twice that of cadaveric transplantation, because it is two people who undertake the surgery, and if the surgery fails, it will affect two people. A person can live a perfectly normal life on one kidney, but having two kidneys is much safer.  What is the possibility of rejection after surgery Except for identical twins, generally patients have to take anti-rejection drugs for life after kidney transplantation to reduce and avoid rejection of the transplanted kidney in the recipient. However, even if the medication is adhered to, rejection is not absolutely avoidable, and the rate of rejection after kidney transplantation in the best international transplant centers is around 15%.  The more common of the rejection reactions is acute rejection. Most of them occur within 6 to 90 days after surgery, but they can be prevented and treated with drugs and most of them can be reversed. The other more common is chronic rejection, which is difficult to detect when it occurs because there are no obvious symptoms in the early stage, and once the symptoms appear, it is already at an advanced stage, and it is difficult to reverse.  What are the advantages of kidney transplantation At present, the only effective treatment for chronic renal failure is kidney transplantation and dialysis treatment. In comparison, it is better to have a kidney transplant if the physical condition allows it, because it can make the quality of life of patients much better. They can live the same life as normal people. Dialysis, on the other hand, requires 2 to 3 treatments per week, which is more painful for patients and can only sustain life, and the disease will not get better and life is very affected. Moreover, the cost of dialysis is higher compared to taking anti-rejection drugs after kidney transplantation.  The cost of doing kidney transplantation is not the same from one hospital to another, and all the costs of the patient from hospitalization to discharge are generally around 50,000 yuan, of course, without serious complications. There are also many varieties of post-operative anti-rejection drugs that patients take, with different prices. Generally speaking, the cost is higher in the first year, and will decrease as the amount of medication is gradually reduced.  As for the time of follow-up after kidney transplantation, it is generally believed that: twice a week in the first month after surgery, once a week in the second month, once every two weeks in the third month, once a month for six months after surgery, once every 1-3 months for 1-2 years after surgery, and once every 3-4 months for more than three years after surgery. The review should be conducted once every 3-4 months.  (1) Accurately reflect to the doctor the self-conscious symptoms, blood pressure, urine volume, appetite, weight change, physical condition, etc.  (2) Blood routine, urine routine, liver function, kidney function, cycloheximide blood concentration, rosette node test, chest X-ray, transplant kidney ultrasound, electrolytes and lipids, etc. if necessary. The specific situation will vary from person to person. Please contact the transplant surgeon frequently to report the situation and review in a timely manner.