Platelet lowering is mainly caused by platelet generation disorder, platelet destruction or excessive consumption, platelet distribution abnormality and other factors. 1. Platelet generation disorder: when the human body has aplastic anemia, acute leukemia, or has been subjected to harmful substances such as benzene, xylene, etc., it will lead to the proliferation, growth and maturation of megakaryocytes in the bone marrow, which will lead to insufficient generation of platelets and a decrease in the number of platelets. 2. Excessive destruction of platelets: For example, the action of drugs such as aminopyrine, sulfonamide, chloramphenicol and other commonly used drugs or infections will cause the body to produce anti-platelet antibodies through the immune mechanism, resulting in a decrease in the number of platelets in the body. 3. Abnormal distribution of platelets: this symptom is mainly seen in hypersplenism or splenomegaly caused by various reasons, and when platelets are blocked too much in the spleen, it will also cause the number of platelets in the blood to decrease significantly. There are many causes of thrombocytopenia, if there are uncomfortable symptoms, patients should go to the hospital in time to receive examination and treatment.