Penicillin drug sensitivity test is generally in the inner forearm, near the wrist part of the local injection of a small amount of penicillin, after injection of penicillin patients should stay in the clinic to observe, half an hour later asked the patient local skin itching, and the whole body with or without other discomfort, to observe the injection site of the skin with or without redness and swelling. Doctors in the use of penicillin need to do the following: 1, to carefully ask the patient has a history of penicillin allergy, allergic to penicillin prohibit the use of penicillin. 2, the use of penicillin should be equipped with rescue medication as well as rescue equipment. 3, the initial interval of more than 3 days, or replacement of penicillin batch number must be done penicillin sensitivity test, the results of the sensitivity of the positive results of the prohibition of the use of penicillin.