The headache after waking up can be relieved in the following ways: First, taking non-steroidal anti-inflammatory drugs, such as compound aminobarbital, indomethacin p-aminosalicylic acid, such as somigotide, depot tablets, ibuprofen, etc., can relieve the headache after waking up from sleep. Second, non-drug means to relieve, usually due to brain hypoxia and insufficient oxygen supply, this will be due to low arterial oxygen saturation and high partial pressure of carbon dioxide, then you can go outdoors and try to breathe deeply to carry out oxygen therapy method, also can go to the hospital to perform oxygen therapy can relieve the headache. Third, insufficient blood supply to the cerebral arteries or coronary arteries of the heart can also lead to headaches after waking up, when you can take compound salvia drops and ginkgo biloba.