The effect of Botox injection is fast, and the effect can be seen gradually in 2-3 days, and the effect can be maximized in 7-12 days. Within seven days, patients can have a tight feeling or an unnatural smile, which is a normal phenomenon and is a manifestation of the effect of the drug, and can recover naturally in about one month. After botulinum toxin injection, it is necessary to maintain an upright position for 4 hours to avoid the spread of the drug, pay attention to keeping the local area dry and hygienic, no water for at least 6 hours, avoid drinking and smoking within a week after injection, avoid eating spicy and stimulating food, avoid strenuous exercise within a week, do not steam sauna or massage to avoid excessive spread of the drug, and do not get pregnant or breastfeed within six months after injection.