Callus on the foot is often due to the bottom of the foot skin by the shoe friction caused by the use of drugs to soften (such as urea cream), frozen peeling, moisturizing agents and other methods to remove. 1. Drug softening: commonly used drugs are 10% urea cream, salicylic acid ointment, petroleum jelly, etc., can be very good to promote the softening of calluses on the soles of the feet, you can also use warm water to soak your feet, soften calluses on the soles of the feet, soften the moisturizing care, apply moisturizing cream. Note that these medications can be applied to the skin may appear localized irritation and other side effects. 2. Freezing peeling: If the patient’s feet callus is thicker, you can go to the hospital to do freezing way to promote peeling, after the operation to keep the skin clean, do not often squeeze the skin of the feet. 3. moisturizing agents: for special occupational groups, need to use more moisturizing agents to alleviate the symptoms, usually also choose loose comfortable shoes, often soak feet. Calluses appear more serious, it is recommended to go to the hospital in time to seek medical attention. The above drugs have adverse reactions, it is recommended to use medication under the guidance of a doctor, do not blindly self-medication to prevent adverse effects.