The phenomenon of 49-year-old woman breasts are getting bigger and bigger, may be the body obesity bra tight, but also may be related to breast hyperplasia, breast fibroids, pituitary tumors and other reasons. 1. Body obesity: 49-year-old women who do not diet, over-eating fat, cholesterol content of food, too little exercise leading to obesity of the body, the breasts are getting bigger and bigger, feel the bra tight. 2. Breast hyperplasia: 49-year-old women with hormonal secretion disorders in the body, abnormal estrogen and progesterone levels, if it leads to severe breast hyperplasia, the breasts may be getting bigger and bigger. 3. Breast Fibroid: 49-year-old women who usually live with too much stress or long-term application of hormonal drugs, endocrine regulation disorders may lead to breast fibroid after the phenomenon of breast enlargement, this situation is usually not bra tight. 4. Pituitary tumors: 49-year-old women who have pituitary tumors and other pituitary gland lesions, resulting in increased prolactin secretion, causing breast development will also be breasts are getting bigger and bigger. The 49-year-old woman appeared the phenomenon of breasts getting bigger and bigger, may also be breast malignant tumors, mastitis, breast trauma and other causes, should go to the hospital, to determine the cause of the disease and then targeted treatment.