The management of vague pain in the right middle abdomen and anal swelling requires symptomatic treatment depending on the cause. Possible causes of this symptom are rectal inflammation, chronic colitis, hemorrhoids co-infection and so on. The main treatment method is medication. 1. Inflammation of the rectum: Hidden pain in the right mid-abdomen accompanied by anal swelling may be due to proctitis leading to inflammation in the intestinal tract, causing abdominal pain and anal swelling. Treatment can use anti-inflammatory drugs such as mesalazine suppositories, antibiotics such as cephalosporin antibiotics for anti-inflammatory symptomatic treatment. 2. Chronic colitis: chronic colitis is also considered the cause of this symptom, for the right lower abdomen of the ascending colon and ileocecal part of the intestinal tract inflammation, causing abdominal pain, anal distension. Probiotics can be used to inhibit acidity and regulate intestinal flora for treatment. 3. Hemorrhoidal co-infection: Hemorrhoidal co-infection may also cause right middle abdominal pain and anal swelling. You can choose iodophor for local disinfection, use potassium permanganate diluted solution for local fumigation, sitz bath cleaning; or use hemorrhoidal suppository anal treatment. If the patient appears right middle abdominal pain, anal swelling, it is recommended to consult a doctor in time, identify the cause of the disease, clear diagnosis, and actively cooperate with the doctor’s treatment.