Radiofrequency ablation for liver cancer eradicates liver cancer, but cannot prevent new liver cancer from occurring. Radiofrequency ablation for liver cancer is a minimally invasive local surgical treatment using thermal effect of radiofrequency current under the guidance of ultrasound or CT, which can inactivate tumor tissues and make tumor tissues necrotic, so as to achieve local eradication of tumors and cause little damage to the surrounding groups of tumors. For radiofrequency ablation for liver cancer, preoperative should be strictly in accordance with the indications of surgery, according to the patient’s age, general condition, and strict implementation of aseptic operation norms. After radiofrequency ablation for hepatocellular carcinoma, patients should pay attention to strengthening nutrition, reasonable diet, rest, appropriate activities, regular rechecking of tumor markers, regular rechecking of ultrasound or CT and other examinations. It is suggested that patients should go to the hospital for consultation and treatment in time and follow the doctor’s instructions, and should not be negligent so as not to delay or aggravate the condition.