Colic is considered to be caused by functional intestinal spasm, and may also be caused by acute gastroenteritis, intussusception and other disease factors. The former need to avoid triggering factors, the latter need to be under the guidance of the doctor to carry out targeted treatment, such as drug therapy, surgical treatment. The pain can be relieved after active treatment. 1. Functional intestinal spasm: adult intestinal spasm patients should avoid overeating, eating too much cold food and other triggers of functional intestinal spasm; children with intestinal spasm should avoid cold, cow’s milk allergy in infants and young children can cause intestinal spasm after consuming cow’s milk, such patients should avoid drinking cow’s milk. At the same time, patients with more severe colic can take pivacurium bromide to relieve spasm and pain, and severe cases can also be injected with resorcinol to relieve symptoms. 2. Acute gastroenteritis: combined with bacterial infection can use ciprofloxacin, levofloxacin and other drugs to fight infection, accompanied by severe abdominal pain can be considered to use scopolamine to relieve pain. 3. Intussusception: if the intussusception occurs within 48 hours, enema therapy can be considered; if it is accompanied by intestinal necrosis or perforation, or if the intussusception lasts more than 48 hours, surgery should be considered. Patients with colic are advised to go to the hospital.