Puncture biopsy and genetic testing can generally be performed at the same time, but they are different programs and should be performed according to your doctor’s recommendations. Puncture biopsy is a medical technique that involves puncturing the body’s tissues under anesthesia to obtain a small number of tissue cells, and then carrying out professional histological diagnosis to clarify the nature of the swelling. Puncture biopsy is generally safe and reliable as it causes less tissue damage and less bleeding. Genetic testing refers to the process of taking human blood, body fluids or tissue cells and then examining the DNA in the cells through specific equipment to analyze the type and expression of genes, which can help to identify the cause of the disease or predict the risk of the body developing a certain disease.