One of the tests performed for hepatitis B is called the five hepatitis B tests, which include a total of five items. According to its normal arrangement, the first item is called hepatitis B surface antigen, the third item is called hepatitis B e antigen, and these two positive items are usually accompanied by positive hepatitis B core antibody, which is one, three, five positive, called the major three, which is a manifestation of the hepatitis B virus is infecting people. This is a sign that the hepatitis B virus is infecting the person. At this time, the hepatitis B virus is often actively replicating, and the DNA quantification of the hepatitis B virus will generally exceed 10^3 copies/mL. Patients with hepatitis B major triple positive are in a state where the hepatitis B virus is infecting people and may have caused related damage to the liver, so liver function, liver ultrasound or other imaging tests and fetoprotein should be checked to determine if there is any related damage to this area. If there is no relevant damage, the patient is a carrier of the hepatitis B virus and currently does not need treatment, but needs to be reviewed regularly. If there is damage, measures should be taken to mitigate the damage and to stop the hepatitis B virus from continuing to cause damage.