Spinal septic infection MRI shows single disc invasion, tuberculosis infection can involve multiple discs, and Mycobacterium brucei infection involves both vertebral body and intervertebral disc. 1. Spinal septic infection: early bacterial infection will enter with the vertebral terminal artery, the typical performance on MRI is a single vertebra or two adjacent vertebrae with T1W low signal, T2W high signal predominantly. After enhancement, the lesion shows obvious diffuse and uniform enhancement. In the later stage, the intervertebral disc destruction is obvious, with T2 obvious high signal and different degrees of enhancement. 2. Tuberculosis infection: Typical tuberculosis spondylitis is manifested in two or more adjacent vertebrae, but the destruction of the corresponding intervertebral discs is dominant, showing low signal on T1WI and mixed signal, high signal or low signal on T2WI. The formation of paravertebral abscess can be ring-shaped enhancement, the border is clear. 3. Borrelia burgdorferi infection: MRI shows that the affected vertebral body and the corresponding intervertebral disc have abnormal signals, the intervertebral disc has increased T2WI signals, and the enhancement scan can be strengthened.