Colon cancer T3N2aM0 belongs to stage IIIb, and the treatment options include surgical treatment, chemotherapy, targeted therapy and so on.
1. Surgery: For colon cancer patients without distant metastasis, radical surgical resection and regional lymph node dissection are the first choice of treatment. If the patient has already had intestinal obstruction and bleeding and is not suitable for surgery temporarily, stent implantation or interventional embolization can be used to stop bleeding, and radical surgery can be considered after the systemic condition is stabilized.
2. Chemotherapy: chemotherapy is an important treatment for progressive colon cancer, which is divided into postoperative chemotherapy and preoperative neoadjuvant chemotherapy. stage IIIb colon cancer patients are recommended to receive adjuvant combined chemotherapy after radical surgery, and the commonly used drugs are 5-fluorouracil, capecitabine, oxaliplatin, etc. Some inoperable patients can receive neoadjuvant chemotherapy after radical surgery, and the most common drugs are 5-fluorouracil, capecitabine and oxaliplatin. Some inoperable patients may have their tumors downgraded after neoadjuvant chemotherapy, which may meet the indication of radical surgery.
3. Targeted therapy: If patients have lost the chance of radical surgery but have sensitive gene mutations, they can also choose targeted therapy, commonly used drugs include bevacizumab and cetuximab. After treatment, some patients’ tumors may be downgraded to a lower stage so that they can undergo surgical treatment.
If stage IIIb colon cancer is detected, it is suggested that patients should go to the hospital as soon as possible, and ask professional doctors to fully evaluate their conditions and decide the specific treatment plan.