Among female menstrual disorders, many are due to abnormal ovulation. In addition to the influence of endocrine glands such as thyroid and adrenal glands, most abnormal ovulation is caused by lesions in the hypothalamus or pituitary gland, which are the superior organs of the ovaries, and ovulation is one of the important functions of the ovaries. Therefore, patients with abnormal ovulation or amenorrhea need to check the function of hypothalamus and pituitary gland. Generally, female hormone measurements can be done, such as high LH and LFH for ovarian amenorrhea, and low E2 for ovarian amenorrhea. For menstruation and ovulation disorders caused by thyroid dysfunction, basal metabolic measurements, serum protein-bound iodine measurements and serum thyroxine (T4) values can be used to check. In the case of adrenocortical dysfunction, which affects ovarian function and causes infertility, urinary hormones, such as 17-ketosteroids and 17-hydroxysteroids, can be determined. Therefore, the cause of menstrual irregularities should be identified.