Luteal insufficiency: There is follicular development and ovulation in the menstrual cycle, but the luteal phase progesterone secretion is insufficient or the luteal function declines prematurely, resulting in poor endocrine response of the uterus. Causes: 1. Poor follicular development 2. Insufficient LH peak secretion 3. Low pulse defect after LH sealing Main manifestations: Menstrual cycle end, frequent; or normal menstrual cycle, but prolonged follicular phase and shortened luteal phase less than 11 days. It often leads to infertility and early pregnancy miscarriage. Treatment: 1. Promote follicular development: Clomiphene or HMG to promote ovulation. 2.Promote peak LH in luteal phase, inject 5000-10000 units of HCG. 3. Luteal function stimulation therapy: HCG 2000 units after ovulation Once every two days. 3-4 times in total. 4.Luteinizing function replacement: progesterone 20-40mg intramuscular injection/day after ovulation. 5. Combined with elevated prolactin: bromocriptine, 1-2 tablets/day.