The main indicators of uremia staging are creatinine and glomerular filtration rate. The term uremia is inaccurate, because uremia is the end stage of the development of chronic renal failure, it is only one of the stages of chronic renal failure, it can not be further staged, and the most accurate way to say it should be the stage of chronic renal failure. The staging of chronic renal failure includes two main indicators, the first, creatinine; the second, glomerular filtration rate. Using creatinine to stage chronic renal failure is the previous method, mainly divided into four stages, namely, compensated renal failure, decompensated renal failure, failure of renal failure and uremic renal failure. The use of creatinine to stage chronic renal failure is not entirely accurate, because creatinine is affected by the patient’s age, weight, gender and other factors, so the glomerular filtration rate is mainly used to stage chronic renal failure. Glomerular filtration rate above 90 ml/min is called stage 1, between 60-90 ml/min is called stage 2, between 30-60 ml/min is called stage 3, between 15-30 ml/min is called stage 4, and below 15 ml/min is called stage 5, also called uremic stage.