The area between the thumb and index finger is called the tiger’s mouth. If pain occurs in the tiger’s mouth area, it may be due to tenosynovitis of the thumb. Commonly, this is stenosing tenosynovitis, which is mainly caused by the patient’s prolonged and heavy activity of the thumb, which leads to a sterile inflammation of the flexor tendon tendon sheath of the thumb, resulting in irritation causing tendon sheath hyperplasia and edema. This can cause symptoms of stenosing tenosynovitis, which can lead to a painful condition with pressure in the middle of the thumb and index finger. It may also be due to an infection in the muscles of the tiger area, causing painful compression. It may be due to an infection of the muscles in the tiger’s mouth after a trauma that is not effectively controlled. Patients can be advised to take anti-infection treatment in time, and when the local infection is controlled, the painful symptoms will be effectively relieved.