Hepatitis B antiviral drugs such as tenofovir and propofol tenofovir can be taken at any time of the day, entecavir needs to be taken on an empty stomach, and is recommended to be taken before bedtime. Most of the hepatitis B antiviral drugs do not have time requirements, such as tenofovir, propofol tenofovir and tibivudine, can be taken at any time of the day, and before and after meals have no effect, but it is generally recommended to be fixed at the same time every day, so as not to miss the medication. Entecavir is special and needs to be taken on an empty stomach in order to be well absorbed, and you can’t eat within two hours of taking the drug, so it’s generally recommended to take the drug before going to bed. The medication should be taken under a doctor’s supervision, and should not be used without authorization.