Always feel the lower limbs are very heavy, very tired, may be related to the following reasons: First, there may be due to long-term non-exercise caused by the lower limbs of the wasting muscle atrophy, this situation in the long-term bedridden or have a long period of sitting and standing work of the most common among the patients. This is most common in patients who have been bedridden or have been sitting or standing for a long time. This kind of patients do not get enough exercise for a long time, resulting in muscle atrophy of the lower limbs, which makes the lower limbs feel weak and heavy. Second, there may be osteoporosis, osteoporosis patients, a large part of the lower limbs show symptoms of heaviness, fatigue. Third, there may be peripheral nerve lesions, such as lumbar disc herniation patients may feel heavy lower limbs, and have obvious weakness. Fourth, there may be some arthritis, if the patient has osteoarthritis of the knee joint, often will also be manifested as lower limb pain, activity limitation, and obvious weakness, limp legs and so on.