Fever after rabies vaccination is generally a normal phenomenon and is one of the adverse reactions to vaccination. Since the vaccine is manufactured with a series of purification processes and relatively few protein impurities, systemic reactions such as fever are rare or mild and are usually not a cause for concern. After rabies vaccination, antibodies are produced in the blood to help prevent rabies virus from proliferating and spreading in the body, and to remove free rabies virus, thus preventing rabies. However, rabies vaccine is a foreign substance to the body, and when injected into the body, the body’s own immune mechanism will respond accordingly, which may lead to uncomfortable symptoms, such as redness, swelling, pain, itching and other reactions at the injection site, and in rare cases, fever, vomiting, dizziness, weakness, diarrhea and a series of other systemic symptoms. These discomfort symptoms after injection usually do not last long and can be relieved in about 2 days. If the body temperature does not exceed 38.5℃, cooling treatment can be carried out by physical means, such as antipyretic patches and ice packs. If the body temperature exceeds 38.5℃, it is recommended to consult a doctor and take relevant antipyretic drugs such as acetaminophen as prescribed by the doctor. In addition, for patients with adverse reactions lasting more than 3 days after vaccination, even if the fever is low, it is still recommended to seek medical attention promptly to prevent secondary infection, etc. Avoid spicy and stimulating food after rabies vaccination, do not recommend drinking strong tea, coffee and other beverages, do not drink alcohol, and do not do strenuous exercise. Keep the area dry and clean, and it is best not to take a bath within 24 hours to prevent infection at the injection site, and pay attention to rest and warmth after vaccination to facilitate recovery.