Pain in the upper chest can be attributed to the following causes: first, diseases of the chest wall, including costochondritis and intercostal neuralgia, which are also seen after trauma or induced by strain and can usually be tolerated, or in severe cases, oral pain medication or combined with nerve-nourishing drugs. Second, some patients have diseases of the chest organs, such as coronary artery disease and myocardial ischemia, and they may have anterior heart pain, chest tightness or panic. The diagnosis can be confirmed by electrocardiogram, and drugs such as nitroglycerin can be given for treatment. Thirdly, mediastinal diseases, commonly thymoma or mediastinal cysts, are purely benign diseases, and patients will have chest tightness and chest pain. In the case of malignant tumors, the patient will also have significant anemia, hypoproteinemia, and will also show signs of depletion. Patients with early diagnosis should also be actively selected for surgical treatment.