Hemifacial shortening is mainly caused by the abnormal development of the first and second gill arches, which often leads to different degrees of hypoplasia or deficiency of the ascending mandibular branch and temporomandibular joint on the affected side, resulting in obvious facial asymmetry. In patients with hemifacial microsomia, the facial height of the affected side is insufficient, the chin is shorter and skewed to the affected side, the occlusal plane is skewed, and the occlusal relationship is disturbed; the soft tissue of the affected side of the cheek is thinner than that of the healthy side; and it is often accompanied by external ear deformity and paronychia. Hemifacial shortening often requires serial treatment. At the age of 2-6 years, mandibular traction osteogenesis is performed, which not only lengthens the underdeveloped mandible but also expands the soft tissues on the affected side. 6-15 years old, orthodontic treatment is performed to help the permanent teeth erupt and grow normally. After the cessation of pubertal development, orthognathic surgery is feasible to correct the deviated jaw and the skewed occlusal plane. For those who do not have enough bone capacity, such as the affected mandible and zygomatic bone, materials should be implanted to correct the lack of fullness on the affected side. If there is also a thin soft tissue on the affected side, autologous fat filler can be performed 3-6 months after surgery to further improve the appearance. For hemifacial atrophy, the typical clinical symptom is progressive atrophy of the soft tissues on the affected side of the face, and the condition usually does not develop after the development of puberty. For mild hemifacial atrophy, which involves only the soft tissues of the face, autologous fat fillers can be performed after puberty. With skeletal insufficiency, artificial implants can be placed on the affected side or (with) zygomatic arch reduction and mandibular osteotomy depending on the situation.