Fresh frozen plasma is a blood product whose main function is to supplement coagulation factors and plasma proteins. Fresh frozen plasma is a blood product made by separating plasma from whole blood within 6 to 8 hours after blood collection or by storing plasma obtained by single collection at -20℃ or even lower. The preservation period is 1 year, and after 1 year, it becomes ordinary frozen plasma. Its advantage is that it can effectively preserve various coagulation factors and plasma proteins. Clinically, it is mainly used for coagulation factor deficiencies caused by various reasons, such as coagulation factor synthesis disorders in liver diseases, relative deficiency of coagulation factors in hemodilution, disseminated intravascular coagulation, as well as bleeding tendency caused by overuse of warfarin, and can also be used for diseases that require supplementation of blood volume and plasma proteins. It should be noted that although plain frozen plasma can also supplement some of the coagulation factors, coagulation factor 5 and coagulation factor 8 are deficient in plain frozen plasma, and in addition the fibrinogen content of plain frozen plasma may be reduced. The use of fresh frozen plasma should be regulated under medical supervision.