The wound infection after 18 days of anal fistula incision surgery can be treated by medication and nursing treatment. 1. medication: patients with wound infection after anal fistula incision surgery, usually can use amoxicillin, levofloxacin and other drugs, such drugs have antibacterial and anti-inflammatory effect, can relieve the wound infection, taking such drugs may appear abdominal pain, nausea, vomiting and other symptoms, allergic to this kind of drug patients are prohibited. 2. Nursing treatment: patients with wound infection can also use warm water sitz bath, or 1:5000 potassium permanganate solution sitz bath, can promote perianal blood circulation, disinfection and anti-inflammatory, reduce bacterial infection, promote wound healing. Normally, we should pay attention to drink more water, eat more easy to digest vegetables and fruits, avoid spicy and stimulating food, while maintaining perianal hygiene and cleanliness, to avoid repeated stimulation of the wound, infection and so on. Patients with postoperative anal fistula infection, should go to the hospital in a timely manner, actively cooperate with the diagnosis and treatment, so as not to delay the condition.