Gui Zhi Tang is contraindicated for those who have external wind-cold with solid surface and no sweating and those who do not meet the indications for the use of the drug, and there are no clear thirteen types of people who should not take Gui Zhi Tang. Gui Zhi Tang is a traditional Chinese medicine formula from the Treatise on Typhoid Fever. The formula consists of Gui Zhi (peeled), Paeoniae Lactiflorae, Ginger (cut), Jujubes (broken), and Glycyrrhiza Glabra (roasted), which is an antidepressant. This formula has the efficacy of detoxifying the muscles and releasing (using sweating and other methods to make the evil qi trapped in the surface of the muscles to go out), harmonizing the camp and guard (making the internal and external qi of the body smooth, each in its own way), and is mainly used for treating the syndrome of deficiency of the surface of the body due to external wind-cold, with the specific symptoms of fever and malignant wind, sweating, headache, dryness of vomiting and rumbling of the nose, whiteness of the moss, lack of thirst, and a floating slow pulse or a weak floating pulse. This formula is often used to treat postpartum or post-disease low fever, vomiting in pregnancy, cold, influenza, low fever of unknown origin, frostbite, urticaria, erythema multiforme, etc. which belongs to Ying-wei disharmony. Note that this formula is contraindicated for those who have external wind-cold sensation with solid surface and no sweating, in addition, there is no other clear contraindication, so there is no thirteen kinds of people who should not take this formula. It should be noted that during the period of taking the medicine, it is forbidden to eat wine, meat, foul smell, sticky, raw and cold things. There is no clear adverse reaction to the use of the medicine. Specific medications related to Gui Zhi Tang should be administered under the guidance of a specialist.