There are two ways of transmission of H. pylori, the first is fecal-oral route and the second is oral-oral route. 1. Fecal-oral route: If the feces of a H. pylori positive patient contaminates food or water, which is then ingested by another person through the mouth and enters the patient’s stomach, the other person will be infected with H. pylori. H. pylori will colonize the stomach and secrete toxins to damage the gastric mucosa. 2. Oral-oral transmission: In normal life, if you have close contact with H. pylori positive patients, such as feeding, kissing, sharing utensils, etc., these close contacts may also cause the spread of H. pylori. To prevent H. pylori infection, you should pay attention to personal hand hygiene, wash your hands before eating, and also reduce the number of meals out, which can reduce the chance of H. pylori transmission.