The most common disease that causes burning sensation in the esophagus is gastroesophageal reflux disease. In terms of medication, it is recommended that the following drugs can be taken orally: 1. Proton pump inhibitors, which are also the most important kind of drugs for this disease, such as rabeprazole, omeprazole, pantoprazole, lansoprazole, etc. 2. Digestive tract motility drugs, such as mosapride, etopride, morpholine, can be used. 3. Drugs that bind bile acid and neutralize gastric acid, such as compound azelmet, magnesium aluminum carbonate, aluminum phosphate 4, in addition, you can also use mucosal protective agents, such as rehabilitation new liquid, glutamine, teprenone, etc. Diet, pay attention to too acidic, too sweet, spicy, irritating things, such as chili peppers, leeks, garlic, groundnuts, etc. are try not to eat. In addition, smoking, alcohol, strong tea, coffee, chocolate, etc., are all influential to this disease.