The skull plays an important role as a protective barrier for the brain, the commander of the body. Therefore, if an accident occurs that causes a skull defect, it can be very dangerous. Cranial defects will firstly cause a very ugly and unattractive appearance; secondly, it is very unsafe, in case of bumps and bruises, brain tissue may be injured, and may even be life-threatening; in addition, it will also lead to unstable intracranial pressure, which affects the circulation of cerebral crematorium, and all intracranial life activities may be affected. Therefore, once a cranial defect occurs, cranial bone repair surgery should be carried out in time. Cranial repair is a very safe procedure and will greatly benefit the patient after the repair. Of course, before doing skull repair surgery, the choice of repair material is very important, good material to achieve better repair results. At present, polyether ether ketone PEEK material is the most ideal cranial bone repair material, because of its various properties are comparable to the autologous cranial bone, almost no difference with the defect before the repair. At present, polyether ether ketone PEEK material has been widely used in clinical cranial bone repair surgery, the clinical effect is very good. PEEK material can achieve nearly perfect shape reset and structural restoration, because it is three-dimensional shaping, 3D printing, general preoperative to the patient to do a cranial three-dimensional reconstruction of ct, that is, cranial CT acquisition of the patient’s head three-dimensional data, and then according to the data for 3D printing, to produce a fully compliant with the patient’s skull structure, structure and structure of the patient’s head, and then the patient’s head, and the patient’s head. PEEK material repair plate that perfectly fits the patient’s cranial structure and the size of the bone window to achieve precise reset.