Eyelid blackening is related to physiological factors, but also with some pathological factors such as adrenocortical insufficiency, drug reactions, eyelid eczema. 1. Physiological factors: excessive eye use, late night, smoking and alcoholism, frequent use of the eyes, aging and other factors can lead to a slowing of venous blood flow, resulting in insufficient blood supply and oxygen supply to the skin of the eye, the metabolites increase in the pigmentation of the eye, thus showing the phenomenon of darkening of the skin of the eye. 2. Pathological factors: metabolic diseases such as adrenocortical insufficiency can lead to insufficient secretion of adrenocorticotropic hormone and increased secretion of melanin, which can lead to localized melanin pigmentation resulting in darkening of the skin. The side effects of some drugs such as Trevoprost can lead to hyperpigmentation. Eczema of the eye skin and other factors can also stimulate the local skin, resulting in the phenomenon of dark eyelids. If the darkening of the eyelids is not relieved by rest, or is accompanied by significant discomfort, you should go to the hospital immediately.