Adult Steele’s disease

  There is no specific diagnostic method for this disease, and it is a diagnosis of exclusion. Many diagnostic or classification criteria have been developed at home and abroad, but there is still no unified and accepted standard. The Cush criteria proposed by the United States in 1977 are recommended for more applications. Diagnostic criteria for adult Still’s disease (Cush criteria): (1) the necessary conditions: ① fever ≥ 39℃; (2) arthritis/arthralgia; (3) rheumatoid factor <1:80; (4) antinuclear antibody <1:100; (2) any two of the following; (1) blood leukocyte count ≥ 15×109/L; (2) rash; (3) pleurisy or pericarditis; (4) hepatomegaly or splenomegaly or generalized superficial lymph node enlargement.  Treatment: Non-steroidal anti-inflammatory drugs (NSAIDs): About 1/4 patients respond well to NSAIDs, and these patients tend to have a better prognosis. Side effects such as hepatotoxicity and intravascular coagulation should be noted during the use of NSAIDs. Systemic glucocorticosteroids should be used in the following cases: (1) NSAIDs are not effective or have toxic side effects such as hepatic impairment or recurrence of disease after dose reduction; (2) severe disease such as pericardial tamponade, myocarditis, severe pneumonia, intravascular coagulation and other serious organ damage. (3) Usually the hormone dose is 0.5~1mg/Kg/d of prednisone, gradually reduce the dose after the symptoms improve, the total course of treatment should not exceed 6 months, the reduction process can be added with non-steroidal drugs to consolidate the efficacy, the poor efficacy or critical condition can be treated with high-dose methylprednisolone shock.  Most patients need to take hormones and add immunosuppressant therapy at the same time, about the role and side effects of hormones and immunosuppressants in my other science, you can refer to, generally are not able to completely stop the drug, need to take a small amount of hormones and or immunosuppressants for life.  There are several diseases that are difficult to treat with Western medicine, one of which is fever of unknown origin, often costing tens of thousands of dollars each time to do various system tests, including bone aspiration, etc., often failing to discover the cause.  In fact, fever is a normal response of the human body. During the evolution of human beings, fever can mobilize the body's immunity to fight against disease and evil, and it is impossible to imagine what would happen to human beings without fever. In adults with Still's disease, fever is often accompanied by a rash, which is parallel to fever, and the rash decreases when the fever subsides, which is actually a way for the body to eliminate heat, just like sweating. For example, if someone invades your home, the best way is to drive him out of your home, not to fight him. Chinese medicine is to expel the evil from the body by expelling the external evil and giving it a way out; Western medicine is to kill the evil in the body, and there is an old saying in Chinese: kill 10,000 enemies and lose 3,000 of your own, the dead bacteria and other metabolites in the body will be followed by a series of other problems.  Each person has different reasons for fever, from the human body's point of view there are fatigue fever, Qi deficiency fever, external fever, Yin deficiency fever, blood deficiency fever and so on, not all can be forced with hormones and immunosuppressants.  Chinese medicine: Chinese medicine has a lot of ways to treat fever, slightly to some understanding of Chinese medicine can name several ways to treat adult STILL disease, Chinese medicine is first bitter and then sweet (the beginning of the disease will fluctuate, but good will be better, generally need 3-6 months each), Western medicine is first sweet and then bitter (with hormones to quickly control the disease, but when to stop the drug is unknown).