Adult Steele’s disease is a difficult disease with a very low incidence, not only difficult to diagnose and treat, but also prone to recurrent attacks. The diagnosis of adult Steele’s disease is based on exclusionary diagnosis, and there is no specific unified diagnostic criteria so far. Even after a clear diagnosis is made, it is still necessary to adjust the medication at any time during the treatment and follow-up to improve the prognosis and pay attention to exclude infections, tumors, hematological diseases and other diseases, so as to revise the diagnosis and treatment plan. Some patients can be cured after treatment; some patients often have recurrent attacks and are difficult to cure; some patients are transformed into rheumatoid arthritis, dermatomyositis, vasculitis or other rheumatic diseases during the treatment process; a small number of patients have poor prognosis due to complications of hemophagocytic syndrome, hematological diseases or malignant tumors. Currently, there are five major categories of drugs commonly used to treat adults with Still’s disease, including non-steroidal anti-inflammatory drugs, immunosuppressants, glucocorticoids, biological agents and traditional Chinese medicine. Among them, they are particularly sensitive to hormones and are most commonly used. Any drug is a double-edged sword, with both advantages and disadvantages. For example, long-term use of non-steroidal analgesics can cause damage to the mucous membrane of the digestive tract, peptic ulcers, damage to liver and kidney function and leukopenia; long-term use of hormones can cause damage to the mucous membrane of the digestive tract, peptic ulcers, aggravation or secondary infection, stimulation of osteoporosis, diabetes, centripetal obesity, necrosis of the femoral head and hyperalgesia; long-term use of immunosuppressants can cause leukopenia, aggravation or secondary infection and damage to liver and kidney function. Long-term use of immunosuppressants can cause leukopenia, aggravation or secondary infection, liver and kidney function damage, etc. Long-term use of biological agents can aggravate or secondary infection, induce tumors, etc. Long-term use of traditional Chinese medicine can also cause the above-mentioned upper gastrointestinal mucous membrane damage, liver damage and other adverse reactions, although various preventive measures have been taken to reduce the occurrence of the above-mentioned adverse reactions in the course of treatment, some patients still experience various adverse reactions. As the saying goes, the treatment should be “three parts treatment, seven parts nourishment”, so it is important not only to use the medicine on time during the treatment, but also to do a good job of personal care. During the treatment period, you should pay attention to the following matters: 1. To prevent the recurrence of the disease during the medication period, you should avoid exertion, keep your mood relaxed, eat a light diet, do not eat spicy stimulating and greasy products, and try not to eat crabs and other seafood. 2. After the symptoms have completely disappeared, do not take it lightly, but still take the medicine for a period of time as prescribed by the doctor.