Doctor, I have a high uric acid in my physical examination, what should I pay attention to? Doctor, my uric acid has been high for many years, but I have no joint pain, does that mean I don’t need treatment? Doctor, I have high blood pressure and high blood cholesterol, and now my uric acid is also high, what should I do? In the clinic, many patients are concerned about “Does asymptomatic hyperuricemia need to be treated?” Do I need to take medicine even if it is not painful?” etc. Nowadays, the prevalence of hyperuricemia is increasing, and it has become the fourth highest after “hypertension”, “hyperglycemia” and “hyperlipidemia”. “It is also a major problem for foodies. Should we deal with hyperuricemia, listen to our answer for you. Internationally, hyperuricemia (HUA) is defined as: 2 fasting blood uric acid levels on non-same day under normal purine diet status, greater than 420μmol/L in men and 360μmol/L in women. it is divided into 3 types according to blood uric acid and uric acid excretion: poor uric acid excretion type, excessive uric acid production type, and mixed type. Therefore, to understand the causes of hyperuricemia, we should measure uric acid levels in addition to regular monitoring of blood uric acid levels for a comprehensive analysis. Hyperuricemia (HUA) is often associated with hypertension, obesity, hyperlipidemia, insulin resistance and other “partners”. 1, hyperuricemia can lead to kidney stones, chronic uric acid nephropathy and increase the risk of kidney failure. 2, patients with hyperuricemia have a 95% increased risk of diabetes compared to normal people, and the mechanism is related to insulin resistance. 3.There is a causal relationship between hyperuricemia and hypertension. A large number of studies have shown that for every 60 μmol/L increase in blood uric acid level, the relative risk of hypertension incidence increases by 13%. 4, hyperuricemia is an independent risk factor for the occurrence of coronary heart disease, heart failure, ischemic stroke and death. Therefore, hyperuricemia must not be taken lightly! A large body of research data suggests that uric acid-lowering therapy for asymptomatic hyperuricemia is beneficial in improving outcomes for complications other than gout. The 2013 Chinese Physician Consensus on the treatment of hyperuricemia and gout suggests that: 1) uric acid-lowering therapy should be started if asymptomatic hyperuricemia is combined with cardiovascular risk factors or cardiovascular and metabolic diseases; 2) uric acid-lowering therapy should also be started if blood uric acid values exceed 540 μmol/L without combined cardiovascular risk factors. The 2014 European League Against Rheumatism (EULAR) guidelines also suggest that those with a first attack of gout at an age younger than 40 years and a blood uric acid level above 480 μmol/L should be actively intervened.