Patients will always be in danger if they do not have their skull repaired in time after a skull defect. It is easy to be injured by external invasion, which is very dangerous and sometimes may even be fatal. Cranial defect may also cause unstable intracranial pressure, the cerebrospinal fluid circulation and blood circulation in the skull are affected, the neurological functions and life activities cannot function normally, and may cause cranial defect syndrome. Most patients also suffer from long-term depression due to the unattractive appearance of the skull. Patients who have undergone cranioplasty have a new cranial bone, which restores the original appearance of the skull and enhances their appearance. In addition, a complete cranial bone can play a strong role in protecting the brain and soft tissues inside the skull by rebuilding a closed and stable cranial cavity environment and ensuring the good operation of intracranial blood circulation, cerebrospinal fluid circulation and various neurological functions. As a major factor affecting the postoperative effect of cranial repair, it is very important to choose the right material. For example, some local hospitals use titanium mesh material for skull repair, and there are uncomfortable symptoms from time to time. For example, the titanium mesh is not insulated and may cause headache and dizziness in hot and cold environments; the titanium mesh overlay repair may cause cutting damage to the scalp at the edges of the material; and the histocompatibility of the titanium mesh is not very good and may cause rejection or postoperative infection, or even scalp tissue destruction, resulting in exposed titanium mesh. If a patient has an exposed titanium mesh, it is advisable to go to the hospital for detailed examination and symptomatic treatment as soon as possible. If necessary, the titanium mesh can be surgically removed and replaced with peek material, which has properties very close to those of human skull bone and is significantly better than traditional titanium mesh.