Dry and bitter mouth in the middle of the night can be relieved by taking some Chinese medicines such as Gentian Liver Pills, Niu Huang Qing Stomach Pills and Huo Xiang Qing Stomach Capsules under the guidance of the doctor. 1. Gentian Liver Pill: composed of gentian, scutellaria, chaihu and gardenia, it has the effect of clearing the liver and gallbladder and facilitating dampness and heat, and can be used for the treatment of liver and gallbladder dampness and heat (dampness and heat are deposited in the liver and gallbladder), tinnitus and deafness, coercive pain and bitterness of the mouth (coercive pain and bitter mouth), dizziness and redness of the eyes (dizziness and redness of the eyes) as well as redness of the urine, etc. It should be noted that the drug is bitter and cold in nature, and long-term use of the drug is easy to hurt the spleen and stomach, so people with weak spleen and stomach should not take it for a long time, and pregnant women and people with cold stomachs should not use it. 2. Niu Huang Qing Stomach Pill: composed of artificial niu huang, chrysanthemum, maitake and mint, it has the effect of clearing the stomach and diarrhea (removing the fire in the stomach), moistening the dryness and laxative effect, and it can be used to treat the symptoms of fire in the heart and stomach, dizziness, swollen and painful gums and sore mouth and tongue, constipation, red urine, etc. It is not recommended for pregnant women. It should be noted that pregnant women should be prohibited from taking the drug. 3. Patchouli Clear Stomach Capsule: composed of patchouli, windbreak, gardenia and hawthorn, it has the efficacy of clearing away heat and dampness, awakening the spleen and eliminating stagnation, and it can be used for the treatment of dyspepsia, epigastric (abdominal) distension and fullness caused by the spleen and stomach fire (the evil of fire encroaching on the spleen and stomach), bitter breath and bad smell, and symptoms of inappetence, etc. When taking this medicine, do not consume it. When taking this medicine, do not eat greasy, cold and indigestible food, and pregnant women are prohibited from taking it. The adverse effects of the above drugs are not clear. When patients experience dry mouth and bitter breath in the middle of the night, it is recommended to take the above medication under the guidance of a doctor, and if any discomfort occurs, stop taking it and go to the hospital for treatment.