Fever and chills, mostly caused by bacterial infections, mycoplasma infections, viral infections, you can take antibacterial drugs, anti-mycoplasma drugs, antipyretic drugs for treatment. 1. Bacterial infections: ① can take penicillin drugs, cephalosporins, macrolides for treatment, such as amoxicillin, cefixime, roxithromycin, etc.; ② high fever can be taken to ibuprofen, acetaminophen for antipyretic treatment. 2. Mycoplasma infection: ① you can take tetracyclines, macrolides, fluoroquinolones antibiotics, such as tetracycline tablets, azithromycin, moxifloxacin, etc.; ② the appearance of high fever symptoms, you can take ibuprofen, acetaminophen for fever reduction treatment. 3. Viral infections: generally self-limiting diseases, can be treated with fever-reducing drugs symptomatic treatment, such as ibuprofen, acetaminophen and so on. These drugs can have side effects such as gastrointestinal irritation, skin rashes, and affecting bone development, and must be taken under the guidance of a doctor in strict accordance with medical advice; in addition, it is important to note that the use of fluoroquinolones is prohibited for children under 18 years of age. When fever and chills occur, you should consult a doctor to find out the cause of the illness and follow the doctor’s instructions to treat the cause.