Rheumatoid arthritis is caused by group A beta-hemolytic streptococcus infection, and the main route of infection is pharyngeal infection. It is recommended that patients can take medication, general measures to regulate. Rheumatoid arthritis is mainly caused by group A group B hemolytic streptococcus infection, some components in group A group B hemolytic streptococcus have the same or similar molecular structure with the joint fluid and synovium, which may produce a cross-immune reaction, thus leading to joint damage. In this case, group A beta-hemolytic streptococcus is mainly caused by infection through the pharynx. Patients with rheumatoid arthritis can use antibiotics such as benzylpenicillin and amoxicillin, as well as non-steroidal anti-inflammatory drugs such as aspirin and diclofenac under the guidance of doctors. In addition, patients should usually pay attention to rest, mainly keep warm, and avoid getting cold or being in a humid environment for a long time. It is recommended that patients with rheumatoid arthritis seek timely medical treatment and standardize the diagnosis and treatment under the guidance of doctors.