White lesions on funduscopic screening are a more serious condition. Funduscopic screening is often used to screen the fundus of the eye in infants, and white lesions on the fundus are commonly seen in familial exudative vitreoretinopathy, retinopathy of prematurity, and infantile retinochoroiditis. Familial exudative vitreoretinopathy is a white lesion that screens in the fundus, a phenomenon that occurs due to the gradual proliferation of fibrous blood vessels in the surrounding retina. Retinopathy of prematurity is a retinal detachment due to lack of oxygen in the retinal tissue of the newborn, so white lesions may appear on funduscopic screening, which can severely affect the child’s vision. Infantile retinochoroiditis may be a more serious condition as the fundus lesions are caused by intrauterine infections during pregnancy and premature labor, which can damage the child’s vision. It is recommended that children with white lesions on fundus screening be seen promptly for evaluation and treatment as prescribed.