The common causes of sore thigh muscles after playing ball are strenuous exercise or muscle strain, which can be relieved by general treatment, physical therapy and medication. 1. Strenuous exercise: it may be due to strenuous exercise, resulting in thigh muscle soreness symptoms. You should pay attention to proper rest and avoid prolonged strenuous exercise. Hot towels can be used to apply hot compresses or appropriate massage to the sore parts, which is conducive to promoting blood circulation, accelerating the discharge of metabolic products, and alleviating the phenomenon of lactic acid accumulation. 2. Muscle strain: may be due to the process of playing ball, thigh force excessive movement, resulting in thigh parts of the acute strain. You should pay attention to rest, suspend playing ball and other sports. If the symptoms of soreness are obvious, you can take oral non-steroidal anti-inflammatory drugs, such as diclofenac sodium, celecoxib, etoricoxib and so on, to relieve the symptoms. Oral medication that activates blood circulation and removes blood stasis, such as Mai Zhi Ling, can also be taken to improve blood circulation after muscle strain, which is conducive to promoting the recovery of thigh muscle strain symptoms. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If the above symptoms occur, it is recommended to go to a regular hospital for early treatment.