Nodules in the right heart diaphragm angle can be caused by inflammation, benign tumors, malignant tumors and other diseases. Inflammation and benign tumors are usually not serious, and those caused by malignant tumors are more serious. 1. Inflammation: right heart diaphragm angle area nodules in the right side of the thoracic cavity base and mediastinum on both sides, located in the heart diaphragm, chest wall and other structures surrounded by the site. When there is chronic inflammation in the right hemidiaphragm angle area, it may lead to lymph node enlargement and formation of nodules, which is usually not serious and can be continued observation and regular review. 2. Benign tumors: Heredity, diet, medication and other reasons may lead to the appearance of benign nodules in the right angular region of the heart diaphragm, usually will not grow significantly and invade other parts of the heart, so it is also considered not serious. 3. Malignant tumors: heredity, infection and other triggers may lead to primary or secondary malignant tumors, which may manifest as right heart diaphragm angle nodule, may appear chest pain, fatigue, low fever and anemia and other symptoms, and may be transferred to other parts of the body, generally more serious. If the examination finds nodules in the right heart diaphragm angle area, further examination of pathological biopsy, chest CT, magnetic resonance and other items are needed to determine the severity and active treatment according to medical advice.